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MLLT10 Break Apart FISH Probe

Empire Genomics’ MLLT10 Break Apart FISH Probe is designed to flank the MLLT10 gene and is typically used for detecting MLLT10 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
MLLT10BA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MLLT10BA-20-AQOR 20 (40 μL) 200 μL
MLLT10BA-20-GOGR 20 (40 μL) 200 μL
MLLT10BA-20-GORE 20 (40 μL) 200 μL
MLLT10BA-20-GRGO 20 (40 μL) 200 μL
MLLT10BA-20-GROR 20 (40 μL) 200 μL
MLLT10BA-20-GRRE 20 (40 μL) 200 μL
MLLT10BA-20-REGO 20 (40 μL) 200 μL
MLLT10BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Gene Details

Gene Symbol: MLLT10

Gene Name: MLLT10, Histone Lysine Methyltransferase DOT1L Cofactor

Chromosome: CHR10: 21823100-22032559

Locus: 10p12.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion Gene

This study investigated a case of myeloid sarcoma (MS), a rare tumor often misdiagnosed as malignant lymphoma, that developed into acute myeloid leukemia (AML). Along with pathologic, morphologic, and immunophenotypic characterization, FISH was used to screen for cytogenetic abnormalities. Our MLLT10 helped detect a rare PICALM-MLLT10 fusion in the patient, an abnormality consistent with disease progression to AML.
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Product Details

Product: MLLT10 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MLLT10-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping